Transgenesis of mammalian PABP reveals mRNA polyadenylation as a general stress response mechanism in bacteria
Summary: In eukaryotes, mRNA 3′-polyadenylation triggers poly(A) binding protein (PABP) recruitment and stabilization. In a stark contrast, polyadenylation marks mRNAs for degradation in bacteria. To study this difference, we trans-express the mammalian nuclear PABPN1 chromosomally and extra-chromos...
Salvato in:
| Autori principali: | , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2021-10-01
|
| Serie: | iScience |
| Soggetti: | |
| Accesso online: | http://www.sciencedirect.com/science/article/pii/S2589004221010877 |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|