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FunOrder: A robust and semi-automated method for the identification of essential biosynthetic genes through computational molecular co-evolution.

Secondary metabolites (SMs) are a vast group of compounds with different structures and properties that have been utilized as drugs, food additives, dyes, and as monomers for novel plastics. In many cases, the biosynthesis of SMs is catalysed by enzymes whose corresponding genes are co-localized in...

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Bibliografiske detaljer
Principais autores: Gabriel A Vignolle, Denise Schaffer, Leopold Zehetner, Robert L Mach, Astrid R Mach-Aigner, Christian Derntl
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2021-09-01
Serier:PLoS Computational Biology
Online adgang:https://doi.org/10.1371/journal.pcbi.1009372
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