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FunOrder: A robust and semi-automated method for the identification of essential biosynthetic genes through computational molecular co-evolution.

Secondary metabolites (SMs) are a vast group of compounds with different structures and properties that have been utilized as drugs, food additives, dyes, and as monomers for novel plastics. In many cases, the biosynthesis of SMs is catalysed by enzymes whose corresponding genes are co-localized in...

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Autores principales: Gabriel A Vignolle, Denise Schaffer, Leopold Zehetner, Robert L Mach, Astrid R Mach-Aigner, Christian Derntl
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2021-09-01
Colección:PLoS Computational Biology
Acceso en línea:https://doi.org/10.1371/journal.pcbi.1009372
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