A Traceless Selection: Counter-selection System That Allows Efficient Generation of Transposon and CRISPR-modified T-cell Products

Recent years have seen major breakthroughs in genome-engineering systems, such as transposon-mediated gene delivery systems and CRISPR-Cas9-mediated genome-editing tools. In these systems, transient expression of auxiliary genes is responsible for permanent genomic modification. For both systems, it...

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Автори:	Riccardo Mezzadra, Andreas Hollenstein, Raquel Gomez-Eerland, Ton N Schumacher
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Elsevier 2016-01-01
Серія:	Molecular Therapy: Nucleic Acids
Предмети:	deletion gene insertion modification
Онлайн доступ:	http://www.sciencedirect.com/science/article/pii/S2162253117300264
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