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Structures of C-mannosylated anti-adhesives bound to the type 1 fimbrial FimH adhesin

Selective inhibitors of the type 1 fimbrial adhesin FimH are recognized as attractive alternatives for antibiotic therapies and prophylaxes against Escherichia coli infections such as urinary-tract infections. To construct these inhibitors, the α-d-mannopyranoside of high-mannose N-glycans, recogniz...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Jerome de Ruyck, Marc F. Lensink, Julie Bouckaert
Hōputu: Artigo
Reo:Inglês
I whakaputaina: International Union of Crystallography 2016-05-01
Rangatū:IUCrJ
Ngā marau:
Urunga tuihono:http://scripts.iucr.org/cgi-bin/paper?S2052252516002487
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