Hdac6 regulates Tip60-p400 function in stem cells
In embryonic stem cells (ESCs), the Tip60 histone acetyltransferase activates genes required for proliferation and silences genes that promote differentiation. Here we show that the class II histone deacetylase Hdac6 co-purifies with Tip60-p400 complex from ESCs. Hdac6 is necessary for regulation of...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
eLife Sciences Publications Ltd
2013-12-01
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| Colección: | eLife |
| Materias: | |
| Acceso en línea: | https://elifesciences.org/articles/01557 |
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