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Differential contribution of p300 and CBP to regulatory element acetylation in mESCs

Abstract Background The transcription coactivators CREB binding protein (CBP) and p300 are highly homologous acetyltransferases that mediate histone 3 lysine 27 acetylation (H3K27ac) at regulatory elements such as enhancers and promoters. Although in most cases, CBP and p300 are considered to be fun...

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Váldodahkkit: Sara Martire, Jennifer Nguyen, Aishwarya Sundaresan, Laura A. Banaszynski
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: BMC 2020-07-01
Ráidu:BMC Molecular and Cell Biology
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Liŋkkat:http://link.springer.com/article/10.1186/s12860-020-00296-9
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