Large-Scale Purification of r28M: A Bispecific scFv Antibody Targeting Human Melanoma Produced in Transgenic Cattle.

<h4>Background</h4>30 years ago, the potential of bispecific antibodies to engage cytotoxic T cells for the lysis of cancer cells was discovered. Today a variety of bispecific antibodies against diverse cell surface structures have been developed, the majority of them produced in mammalian cell cult...

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Autores principales:	Katrin Spiesberger, Florian Paulfranz, Anton Egger, Judith Reiser, Claus Vogl, Judith Rudolf-Scholik, Corina Mayrhofer, Ludger Grosse-Hovest, Gottfried Brem
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Public Library of Science (PLoS) 2015-01-01
Colección:	PLoS ONE
Acceso en línea:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0140471&type=printable
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