Enhancing soluble expression and purification of a bispecific scFv antibody in Escherichia coli using chaperones
Background and purpose: The use of a bispecific antibody engineered as a tandem single-chain fragment variable antibody (scFv-BsAb) offers several advantages over full-length antibodies, including enhanced tissue penetration and the potential for production in bacterial cells. However, production of...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Wolters Kluwer Medknow Publications
2026-05-01
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| Collection: | Research in Pharmaceutical Sciences |
| Sujets: | |
| Accès en ligne: | https://journals.lww.com/10.4103/RPS.RPS_10_24 |
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