Anticalin N- or C-Terminal on a Monoclonal Antibody Affects Both Production and In Vitro Functionality

Bispecific antibodies (BsAbs) represent an important advance in innovative therapeutic strategies. Among the countless formats of BsAbs, fusion with molecules such as anticalins linked to a monoclonal antibody (mAb), represents an easy and low-cost way to obtain innovative molecules. We fused an ant...

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Váldodahkkit:	Nicolas Aubrey, Valérie Gouilleux-Gruart, Christine Dhommée, Julie Mariot, Fanny Boursin, Nicolas Albrecht, Cécile Bergua, Cécile Croix, Mäelle Gilotin, Eloi Haudebourg, Catherine Horiot, Laetitia Matthias, Caroline Mouline, Laurie Lajoie, Audrey Munos, Gilles Ferry, Marie-Claude Viaud-Massuard, Gilles Thibault, Florence Velge-Roussel
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	MDPI AG 2022-08-01
Ráidu:	Antibodies
Fáttát:	monoclonal antibody bispecific antibody anticalin Fc gamma receptors FcRn CD16
Liŋkkat:	https://www.mdpi.com/2073-4468/11/3/54
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