Optimized production of a truncated form of the recombinant neuraminidase of influenza virus in Escherichia coli as host with suitable functional activity

Abstract Background To discover effective drugs for treating Influenza (a disease with high annual mortality), large amounts of recombinant neuraminidase (NA) with suitable catalytic activity are needed. However, the functional activity of the full-length form of this enzyme in the bacterial host (a...

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Bibliografische Detailangaben

Hauptverfasser:	Fatemeh Sadat Shariati, Fatemeh Fotouhi, Behrokh Farahmand, Zahra Barghi, Kayhan Azadmanesh
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2024-11-01
Schriftenreihe:	Microbial Cell Factories
Schlagworte:	Truncated neuraminidase Influenza virus H1N1 Soluble neuraminidase expression Central composite design SILEX systems
Online-Zugang:	https://doi.org/10.1186/s12934-024-02587-8
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