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Exploring the chemical space of influenza neuraminidase inhibitors

The fight against the emergence of mutant influenza strains has led to the screening of an increasing number of compounds for inhibitory activity against influenza neuraminidase. This study explores the chemical space of neuraminidase inhibitors (NAIs), which provides an opportunity to obtain furthe...

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Principais autores: Nuttapat Anuwongcharoen, Watshara Shoombuatong, Tanawut Tantimongcolwat, Virapong Prachayasittikul, Chanin Nantasenamat
פורמט: Artigo
שפה:Inglês
יצא לאור: PeerJ Inc. 2016-04-01
סדרה:PeerJ
נושאים:
Influenza
Neuraminidase
Neuraminidase inhibitor
Chemical space
QSAR
Scaffold analysis
גישה מקוונת:https://peerj.com/articles/1958.pdf
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