IDH2 deficiency enhances ferroptosis-induced vascular inflammation and remodeling in diabetes
Abstract Endothelial dysfunction is a central feature of vascular complications in type 2 diabetes mellitus (T2DM). Given that ferroptosis contributes to endothelial injury in metabolic disorders, we investigated the role of isocitrate dehydrogenase 2 (IDH2) in regulating endothelial ferroptosis und...
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| Principais autores: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2026-05-01
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| Serier: | Scientific Reports |
| Fag: | |
| Online adgang: | https://doi.org/10.1038/s41598-026-50478-2 |
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