IDH2 deficiency enhances ferroptosis-induced vascular inflammation and remodeling in diabetes
Abstract Endothelial dysfunction is a central feature of vascular complications in type 2 diabetes mellitus (T2DM). Given that ferroptosis contributes to endothelial injury in metabolic disorders, we investigated the role of isocitrate dehydrogenase 2 (IDH2) in regulating endothelial ferroptosis und...
Shranjeno v:
| Principais autores: | , , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Portfolio
2026-05-01
|
| Serija: | Scientific Reports |
| Teme: | |
| Online dostop: | https://doi.org/10.1038/s41598-026-50478-2 |
| Oznake: |
Brez oznak, prvi označite!
|