The HIV-1 envelope cytoplasmic tail protects infected cells from ADCC by downregulating CD4
ABSTRACT HIV-1-mediated CD4 downregulation is a well-known mechanism that protects infected cells from antibody-dependent cellular cytotoxicity (ADCC). While CD4 downregulation by HIV-1 Nef and Vpu proteins has been extensively studied, the contribution of the HIV-1 envelope glycoprotein (Env) in th...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2025-10-01
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| Serie: | mBio |
| Soggetti: | |
| Accesso online: | https://journals.asm.org/doi/10.1128/mbio.01763-25 |
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