क्यूआर कोड

The HIV-1 envelope cytoplasmic tail protects infected cells from ADCC by downregulating CD4

ABSTRACT HIV-1-mediated CD4 downregulation is a well-known mechanism that protects infected cells from antibody-dependent cellular cytotoxicity (ADCC). While CD4 downregulation by HIV-1 Nef and Vpu proteins has been extensively studied, the contribution of the HIV-1 envelope glycoprotein (Env) in th...

पूर्ण विवरण

में बचाया:
मुख्य लेखकों: Alexandra Tauzin, Étienne Bélanger, Jérémie Prévost, Halima Medjahed, Catherine Bourassa, Frederic Bibollet-Ruche, Jonathan Richard, Beatrice H. Hahn, Andrés Finzi
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2025-10-01
श्रृंखला:mBio
विषय:
HIV-1
Env
cytoplasmic tail
CD4
ADCC
CD4-induced antibodies
ऑनलाइन पहुंच:https://journals.asm.org/doi/10.1128/mbio.01763-25
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