A multiplex Mtb-specific FluoroSpot assay measuring IFNγ, IL-2, and TNF-secreting cells can improve accuracy and differentiation across the tuberculosis spectrum

ABSTRACT Tuberculosis (TB) remains a major global health challenge, with current diagnostic tools unable to reliably distinguish between individuals at different stages of the TB spectrum of infection (TBI) and disease (TBD). Interferon-gamma release assays (IGRAs), while commonly used, are limited...

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Xehetasun bibliografikoak

Egile Nagusiak:	Elin Folkesson, Fariba Foroogh, Linn Kleberg, Vera Kjellgren, Mathilda Jakobsson, Lisann Grunewald, Jens Hellberg, Jennifer Ryberg, Zahra Maher, Carolina Sousa Silva, Maia S. Gower, Hans Grönlund, Margarida Correia-Neves, Bartek Makower, Gunilla Källenius, Judith Bruchfeld, Christopher Sundling
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology 2025-12-01
Saila:	Journal of Clinical Microbiology
Gaiak:	tuberculosis mycobacterium diagnostics T cells cytokines immuno-assay
Sarrera elektronikoa:	https://journals.asm.org/doi/10.1128/jcm.00894-25
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