A multiplex Mtb-specific FluoroSpot assay measuring IFNγ, IL-2, and TNF-secreting cells can improve accuracy and differentiation across the tuberculosis spectrum

ABSTRACT Tuberculosis (TB) remains a major global health challenge, with current diagnostic tools unable to reliably distinguish between individuals at different stages of the TB spectrum of infection (TBI) and disease (TBD). Interferon-gamma release assays (IGRAs), while commonly used, are limited...

Descripción completa

Detalles Bibliográficos

Autores principales:	Elin Folkesson, Fariba Foroogh, Linn Kleberg, Vera Kjellgren, Mathilda Jakobsson, Lisann Grunewald, Jens Hellberg, Jennifer Ryberg, Zahra Maher, Carolina Sousa Silva, Maia S. Gower, Hans Grönlund, Margarida Correia-Neves, Bartek Makower, Gunilla Källenius, Judith Bruchfeld, Christopher Sundling
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology 2025-12-01
Colección:	Journal of Clinical Microbiology
Materias:	tuberculosis mycobacterium diagnostics T cells cytokines immuno-assay
Acceso en línea:	https://journals.asm.org/doi/10.1128/jcm.00894-25
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!