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Extending ImmunoSpot<sup>®</sup> Assays’ Sensitivity for Detecting Rare Antigen-Specific B Cells to One in a Million—And Possibly Lower

<b>Background/Objectives</b>: Despite clonal expansion during a primary immune response, or after subsequent antigen encounters, the frequency of memory B cells (B<sub>mem</sub>) specific for an antigen remains low, making their detection difficult. However, unlike serum antibodies, which have a sho...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Greg A. Kirchenbaum, Noémi Becza, Lingling Yao, Alexey Y. Karulin, Paul V. Lehmann
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: MDPI AG 2026-01-01
Sraith:Vaccines
Ábhair:
Rochtain ar líne:https://www.mdpi.com/2076-393X/14/1/88
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