Extending ImmunoSpot^® Assays’ Sensitivity for Detecting Rare Antigen-Specific B Cells to One in a Million—And Possibly Lower

<b>Background/Objectives</b>: Despite clonal expansion during a primary immune response, or after subsequent antigen encounters, the frequency of memory B cells (B_mem) specific for an antigen remains low, making their detection difficult. However, unlike serum antibodies, which have a sho...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Greg A. Kirchenbaum, Noémi Becza, Lingling Yao, Alexey Y. Karulin, Paul V. Lehmann
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	MDPI AG 2026-01-01
Σειρά:	Vaccines
Θέματα:	ELISPOT FluoroSpot immunological memory cross-reactivity Ig class diagnostics
Διαθέσιμο Online:	https://www.mdpi.com/2076-393X/14/1/88
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