Mitochondrial activity promotes neutrophil degranulation and endothelial dysfunction in systemic infections
Abstract Neutrophils are essential for defense against pathogens but excessive activation in systemic infections can drive immunopathology. We show that neutrophil degranulation can induce endothelial dysfunction via degradation of the glycocalyx and increase of endothelial permeability. To identify...
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| Główni autorzy: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Springer Nature
2026-05-01
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| Seria: | EMBO Molecular Medicine |
| Dostęp online: | https://doi.org/10.1038/s44321-026-00453-1 |
| Etykiety: |
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