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New Marine Fungal Deoxy-14,15-Dehydroisoaustamide Resensitizes Prostate Cancer Cells to Enzalutamide

Marine fungi serve as a valuable source for new bioactive molecules bearing various biological activities. In this study, we report on the isolation of a new indole diketopiperazine alkaloid deoxy-14,15-dehydroisoaustamide (<b>1</b>) from the marine-derived fungus <i>Penicillium dimorphosporum</i> K...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Sergey A. Dyshlovoy, Olesya I. Zhuravleva, Jessica Hauschild, Tobias Busenbender, Dmitry N. Pelageev, Anton N. Yurchenko, Yuliya V. Khudyakova, Alexandr S. Antonov, Markus Graefen, Carsten Bokemeyer, Gunhild von Amsberg
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2023-01-01
Schriftenreihe:Marine Drugs
Schlagworte:
<i>Penicillium dimorphosporum</i>
secondary metabolites
prenylated indole alkaloid
prostate cancer
androgen receptor
enzalutamide
Online-Zugang:https://www.mdpi.com/1660-3397/21/1/54
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