Recombinant Human Fab Antibodies Differentially Neutralize Shiga Toxin in Renal Epithelial and Endothelial Cells

Hemolytic Uremic Syndrome (HUS) is a severe clinical manifestation primarily triggered by Shiga toxin-producing <i>Escherichia coli</i> (STEC). While Shiga toxins (Stx) are central to the development of systemic endothelial damage, current recombinant antibody developments have overwhelmingly focuse...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Fernando D. Gómez, Daniela Luz, Isabel Chinen, Daniel Girón, Raissa L. Ferreira, Camila Henrique, Ariela O. P. Bom, Izabella M. Henrique, Wanderson Marques da Silva, Flavia Sacerdoti, Elizabeth S. Miliwebsky, Gang Chen, Claudia C. Carbonari, Sachdev S. Sidhu, Roxane M. F. Piazza, María Marta Amaral
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2026-06-01
coleção:	Toxins
Assuntos:	Shiga toxin STEC Fabs hemolytic uremic syndrome toxin neutralization
Acesso em linha:	https://www.mdpi.com/2072-6651/18/6/257
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!