Recombinant Human Fab Antibodies Differentially Neutralize Shiga Toxin in Renal Epithelial and Endothelial Cells

Hemolytic Uremic Syndrome (HUS) is a severe clinical manifestation primarily triggered by Shiga toxin-producing <i>Escherichia coli</i> (STEC). While Shiga toxins (Stx) are central to the development of systemic endothelial damage, current recombinant antibody developments have overwhelmingly focuse...

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Autori principali:	Fernando D. Gómez, Daniela Luz, Isabel Chinen, Daniel Girón, Raissa L. Ferreira, Camila Henrique, Ariela O. P. Bom, Izabella M. Henrique, Wanderson Marques da Silva, Flavia Sacerdoti, Elizabeth S. Miliwebsky, Gang Chen, Claudia C. Carbonari, Sachdev S. Sidhu, Roxane M. F. Piazza, María Marta Amaral
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2026-06-01
Serie:	Toxins
Soggetti:	Shiga toxin STEC Fabs hemolytic uremic syndrome toxin neutralization
Accesso online:	https://www.mdpi.com/2072-6651/18/6/257
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