Recombinant Human Fab Antibodies Differentially Neutralize Shiga Toxin in Renal Epithelial and Endothelial Cells

Hemolytic Uremic Syndrome (HUS) is a severe clinical manifestation primarily triggered by Shiga toxin-producing <i>Escherichia coli</i> (STEC). While Shiga toxins (Stx) are central to the development of systemic endothelial damage, current recombinant antibody developments have overwhelmingly focuse...

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Bibliografski detalji

Glavni autori:	Fernando D. Gómez, Daniela Luz, Isabel Chinen, Daniel Girón, Raissa L. Ferreira, Camila Henrique, Ariela O. P. Bom, Izabella M. Henrique, Wanderson Marques da Silva, Flavia Sacerdoti, Elizabeth S. Miliwebsky, Gang Chen, Claudia C. Carbonari, Sachdev S. Sidhu, Roxane M. F. Piazza, María Marta Amaral
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2026-06-01
Serija:	Toxins
Teme:	Shiga toxin STEC Fabs hemolytic uremic syndrome toxin neutralization
Online pristup:	https://www.mdpi.com/2072-6651/18/6/257
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