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Mitochondrial apolipoprotein A-I binding protein alleviates atherosclerosis by regulating mitophagy and macrophage polarization

Abstract Apolipoprotein A-I binding protein (AIBP), a secreted protein, has been shown to play a pivotal role in the development of atherosclerosis. The function of intracellular AIBP, however, is not yet well characterized. Here, we found that AIBP is abundantly expressed within human and mouse ath...

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Principais autores: Meng Duan, Hainan Chen, Linjie Yin, Xiao Zhu, Petr Novák, Yuncheng Lv, Guojun Zhao, Kai Yin
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2022-05-01
coleção:Cell Communication and Signaling
Assuntos:
AIBP
Mitophagy
Atherosclerosis
Macrophage polarization
Acesso em linha:https://doi.org/10.1186/s12964-022-00858-8
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