Structural analogs of pulmonary surfactant phosphatidylglycerol inhibit toll-like receptor 2 and 4 signaling

The pulmonary surfactant phospholipid, 1-palmitoyl-2-oleoylphosphatidylglycerol (POPG), potently inhibits toll-like receptor (TLR)2 and TLR4 signaling from the cell surface of macrophages. Analogs of POPG that vary in polar head group length, hydroxylation, and alkyl branching were synthesized using...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Pitchaimani Kandasamy, Mari Numata, Karin Zemski Berry, Rachel Fickes, Christina C. Leslie, Robert C. Murphy, Dennis R. Voelker
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2016-06-01
Colecção:	Journal of Lipid Research
Assuntos:	anti-inflammatory endotoxin eicosanoids
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0022227520351774
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!