Hydrolysis and depletion of phosphatidylglycerol at peak murine acute lung injury

Anionic phospholipids are essential for surfactant function and phosphatidylglycerol (PG) is the most abundant. Increased secretory phospholipase A2 (sPLA2) and disproportionate depletion of PG is consistently observed in patients with acute respiratory distress syndrome (ARDS), leading to speculati...

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Библиографические подробности

Главные авторы:	Brandon Baer, Michael C. Seeds, Michael V. Novotny, Matthew J. Satusky, Christopher M. Lloyd, Barbara Olmeda, Jesus Perez-Gil, R. Duncan Hite
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Elsevier 2026-07-01
Серии:	Journal of Lipid Research
Предметы:	acute respiratory distress syndrome acute lung injury pulmonary surfactant phosphatidylglycerol secretory phospholipase A2 surface tension
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S0022227526000945
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