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A brief review of Lynch syndrome: understanding the dual cancer risk between endometrial and colorectal cancer

Lynch syndrome (LS) is an autosomal dominant disorder caused by germline mutations in DNA mismatch repair (MMR) genes. These mutations result in frameshift alterations, leading to the accumulation of errors within microsatellites. Individuals with LS have an elevated risk of developing colorectal an...

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Detaylı Bibliyografya
Asıl Yazarlar: Sneha Pallatt, Sibin Nambidi, Subhamay Adhikary, Antara Banerjee, Surajit Pathak, Asim K. Duttaroy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2025-05-01
Seri Bilgileri:Oncology Reviews
Konular:
Online Erişim:https://www.frontiersin.org/articles/10.3389/or.2025.1549416/full
Etiketler: Etiketle
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