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Tetramer stability and functional regulation of tumor suppressor protein p53
This thesis presents the first report of the comprehensive and quantitative analysis of the effects of tumor-derived mutations on the tetrameric structure of tumor suppressor protein p53, which plays a central role in maintaining genomic integrity. Inactivation of p53 via mutation of its gene is a k...
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| Autor principal: | |
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| Formato: | Livro |
| Idioma: | Inglês |
| Publicado em: |
Springer,
c201
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| Colecção: | Springer theses, recognizing outstanding ph.d. research |
| Assuntos: | |
| Acesso em linha: | https://minerva.ufrj.br/F/?func=direct&doc_number=000946418&local_base=UFR01 |
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