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Tumor Suppressor p53 Slides on DNA with Low Friction and High Stability
The p53 protein, a transcription factor of key importance in tumorigenesis, is suggested to diffuse one-dimensionally along DNA via its C-terminal domain, a process that is proposed to regulate gene activation both positively and negatively. There has been no direct observation of p53 moving along D...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2426630/ https://ncbi.nlm.nih.gov/pubmed/18424488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.134122 |
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