Methodological aspects of the oxygenscan in sickle cell disease: A need for standardization

по Rab, Minke A.E., Kanne, Celeste K., Bos, Jennifer, Boisson, Camille, van Oirschot, Brigitte A., Nader, Elie, Renoux, Céline, Joly, Philippe, Fort, Romain, van Beers, Eduard J., Sheehan, Vivien A., van Wijk, Richard, Connes, Philippe
Опубликовано в: Am J Hematol (2019)

AG-348 (mitapivat), an allosteric activator of red blood cell pyruvate kinase, increases enzymatic activity, protein stability, and adenosine triphosphate levels over a broad range...

по Rab, Minke A.E., van Oirschot, Brigitte A., Kosinski, Penelope A., Hixon, Jeffrey, Johnson, Kendall, Chubukov, Victor, Dang, Lenny, Pasterkamp, Gerard, van Straaten, Stephanie, van Solinge, Wouter W., van Beers, Eduard J., Kung, Charles, van Wijk, Richard
Опубликовано в: Haematologica (2020)

Decreased activity and stability of pyruvate kinase in sickle cell disease: a novel target for mitapivat therapy

по Rab, Minke A. E., Bos, Jennifer, van Oirschot, Brigitte A., van Straaten, Stephanie, Kosinski, Penelope A., Chubukov, Victor, Kim, Hyeryun, Mangus, Heidi, Schutgens, Roger E. G., Pasterkamp, Gerard, Dang, Lenny, Kung, Charles, van Beers, Eduard J., van Wijk, Richard
Опубликовано в: Blood (2021)

The fluid membrane determines mechanics of erythrocyte extracellular vesicles and is softened in hereditary spherocytosis

по Vorselen, Daan, van Dommelen, Susan M., Sorkin, Raya, Piontek, Melissa C., Schiller, Jürgen, Döpp, Sander T., Kooijmans, Sander A. A., van Oirschot, Brigitte A., Versluijs, Birgitta A., Bierings, Marc B., van Wijk, Richard, Schiffelers, Raymond M., Wuite, Gijs J. L., Roos, Wouter H.
Опубликовано в: Nat Commun (2018)

Ribosomal Protein Mutations Induce Autophagy through S6 Kinase Inhibition of the Insulin Pathway

по Heijnen, Harry F., van Wijk, Richard, Pereboom, Tamara C., Goos, Yvonne J., Seinen, Cor W., van Oirschot, Brigitte A., van Dooren, Rowie, Gastou, Marc, Giles, Rachel H., van Solinge, Wouter, Kuijpers, Taco W., Gazda, Hanna T., Bierings, Marc B., Da Costa, Lydie, MacInnes, Alyson W.
Опубликовано 2014

Rapid and reproducible characterization of sickling during automated deoxygenation in sickle cell disease patients

по Rab, Minke A.E., van Oirschot, Brigitte A., Bos, Jennifer, Merkx, Tesy H., van Wesel, Annet C.W., Abdulmalik, Osheiza, Safo, Martin K., Versluijs, Birgitta A., Houwing, Maite E., Cnossen, Marjon H., Riedl, Jurgen, Schutgens, Roger E.G., Pasterkamp, Gerard, Bartels, Marije, van Beers, Eduard J., van Wijk, Richard
Опубликовано в: Am J Hematol (2019)

Oxygen gradient ektacytometry‐derived biomarkers are associated with vaso‐occlusive crises and correlate with treatment response in sickle cell disease

по Rab, Minke A. E., Kanne, Celeste K., Bos, Jennifer, van Oirschot, Brigitte A., Boisson, Camille, Houwing, Maite E., Gerritsma, Jorn, Teske, Erik, Renoux, Celine, Riedl, Jurgen, Schutgens, Roger E. G., Bartels, Marije, Nur, Erfan, Joly, Philippe, Fort, Romain, Cnossen, Marjon H., van Wijk, Richard, Connes, Philippe, van Beers, Eduard J., Sheehan, Vivien A.
Опубликовано в: Am J Hematol (2020)

Effects of Genotypes and Treatment on Oxygenscan Parameters in Sickle Cell Disease

по Boisson, Camille, Rab, Minke A. E., Nader, Elie, Renoux, Céline, Kanne, Celeste, Bos, Jennifer, van Oirschot, Brigitte A., Joly, Philippe, Fort, Romain, Gauthier, Alexandra, Stauffer, Emeric, Poutrel, Solene, Kebaili, Kamila, Cannas, Giovanna, Garnier, Nathalie, Renard, Cécile, Hequet, Olivier, Hot, Arnaud, Bertrand, Yves, van Wijk, Richard, Sheehan, Vivien A., van Beers, Eduard J., Connes, Philippe
Опубликовано в: Cells (2021)