Cathepsin D is the main lysosomal enzyme involved in the degradation of α-synuclein and generation of its carboxy-terminally truncated species

Por Sevlever, Daniel, Jiang, Peizhou, Yen, Shu-Hui C.
Publicado em 2008

Dopamine prevents lipid peroxidation-induced accumulation of toxic α-synuclein oligomers by preserving autophagy-lysosomal function

Por Jiang, Peizhou, Gan, Ming, Yen, Shu-Hui C.
Publicado em 2013

Immunocytochemical Studies of Neurofibrillary Tangles

Por Yen, Shu-Hui C., Gaskin, Felicia, Terry, Robert D.
Publicado em 1981

Nutrient deprivation induces α-synuclein aggregation through endoplasmic reticulum stress response and SREBP2 pathway

Por Jiang, Peizhou, Gan, Ming, Lin, Wen-Lang, Yen, Shu-Hui C.
Publicado em 2014

Aggregates Assembled from Overexpression of Wild Type α-Synuclein Are Not Toxic to Human Neuronal Cells

Por Ko, Li-wen, Ko, Hwai-hwa C., Lin, Wen-Lang, Kulathingal, Jayanranyan G., Yen, Shu-Hui C.
Publicado em 2008

ER stress response plays an important role in aggregation of α-synuclein

Por Jiang, Peizhou, Gan, Ming, Ebrahim, Abdul Shukkur, Lin, Wen-Lang, Melrose, Heather L, Yen, Shu-Hui C
Publicado em 2010

AMPK over-activation leads to accumulation of α-synuclein oligomers and decrease of neurites

Por Jiang, Peizhou, Gan, Ming, Ebrahim, Abdul Shukkur, Castanedes-Casey, Monica, Dickson, Dennis W., Yen, Shu-Hui C.
Publicado em 2012

Corticobasal degeneration with olivopontocerebellar atrophy and TDP-43 pathology: an unusual clinicopathologic variant of CBD

Por Kouri, Naomi, Oshima, Kenichi, Takahashi, Makio, Murray, Melissa E., Ahmed, Zeshan, Parisi, Joseph E., Yen, Shu-Hui C., Dickson, Dennis W.
Publicado em 2013