Lck bound to coreceptor is less active than free Lck

by Wei, Qianru, Brzostek, Joanna, Sankaran, Shvetha, Casas, Javier, Hew, Lois Shi-Qi, Yap, Jiawei, Zhao, Xiang, Wojciech, Lukasz, Gascoigne, Nicholas R. J.
Published in Proc Natl Acad Sci U S A (2020)

Themis-associated phosphatase activity controls signaling in T cell development

by Mehta, Monika, Brzostek, Joanna, Chen, Elijah W., Tung, Desmond W. H., Chen, Shuting, Sankaran, Shvetha, Yap, Jiawei, Rybakin, Vasily, Gascoigne, Nicholas R. J.
Published in Proc Natl Acad Sci U S A (2018)

Expansion of an Unusual Virtual Memory CD8(+) Subpopulation Bearing Vα3.2 TCR in Themis-Deficient Mice

by Prasad, Mukul, Wojciech, Lukasz, Brzostek, Joanna, Hu, Jianfang, Chua, Yen Leong, Tung, Desmond Wai Hon, Yap, Jiawei, Rybakin, Vasily, Gascoigne, Nicholas R. J.
Published in Front Immunol (2021)

Targeting CAR to the Peptide-MHC Complex Reveals Distinct Signaling Compared to That of TCR in a Jurkat T Cell Model

by Wu, Ling, Brzostek, Joanna, Sankaran, Shvetha, Wei, Qianru, Yap, Jiawei, Tan, Triscilla Y.Y., Lai, Junyun, MacAry, Paul A., Gascoigne, Nicholas R. J.
Published in Cancers (Basel) (2021)

Nonstimulatory peptide–MHC enhances human T-cell antigen-specific responses by amplifying proximal TCR signaling

by Zhao, Xiang, Sankaran, Shvetha, Yap, Jiawei, Too, Chien Tei, Ho, Zi Zong, Dolton, Garry, Legut, Mateusz, Ren, Ee Chee, Sewell, Andrew K., Bertoletti, Antonio, MacAry, Paul A., Brzostek, Joanna, Gascoigne, Nicholas R. J.
Published in Nat Commun (2018)

Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01

by Gu, Yue, Wong, Yee Hwa, Liew, Chong Wai, Chan, Conrad E. Z., Murali, Tanusya M., Yap, Jiawei, Too, Chien Tei, Purushotorman, Kiren, Hamidinia, Maryam, El Sahili, Abbas, Goh, Angeline T. H., Teo, Rachel Z. C., Wood, Kathryn J., Hanson, Brendon J., Gascoigne, Nicholas R. J., Lescar, Julien, Vathsala, Anantharaman, MacAry, Paul A.
Published in Nat Commun (2019)