Tissue Reservoirs of HIV

by Wong, Joseph K., Yukl, Steven A.
Published in Curr Opin HIV AIDS (2016)

Advantages of using the QIAshredder instead of restriction digestion to prepare DNA for droplet digital PCR

by Yukl, Steven A., Kaiser, Philipp, Kim, Peggy, Li, Peilin, Wong, Joseph K.
Published in Biotechniques (2014)

Characterization of the HIV-1 transcription profile after romidepsin administration in ART-suppressed individuals

by MORON-LOPEZ, Sara, KIM, Peggy, SøGAARD, Ole S., TOLSTRUP, Martin, WONG, Joseph K., YUKL, Steven A.
Published in AIDS (2019)

HIV latency in isolated patient CD4(+) T cells may be due to blocks in HIV transcriptional elongation, completion, and splicing

by Yukl, Steven A., Kaiser, Philipp, Kim, Peggy, Telwatte, Sushama, Joshi, Sunil K., Vu, Mai, Lampiris, Harry, Wong, Joseph K.
Published in Sci Transl Med (2018)

Assays for precise quantification of total (including short) and elongated HIV-1 transcripts

by Kaiser, Philipp, Joshi, Sunil K., Kim, Peggy, Li, Peilin, Liu, Hongbing, Rice, Andrew P., Wong, Joseph K., Yukl, Steven A.
Published in J Virol Methods (2016)

Stimulating the RIG-I pathway to kill cells in the latent HIV reservoir following viral reactivation

by Li, Peilin, Kaiser, Philipp, Lampiris, Harry W., Kim, Peggy, Yukl, Steven A., Havlir, Diane V., Greene, Warner C., Wong, Joseph K.
Published in Nat Med (2016)

Novel RT-ddPCR Assays for determining the transcriptional profile of SARS-CoV-2

by Telwatte, Sushama, Kumar, Nitasha, Vallejo-Gracia, Albert, Kumar, G. Renuka, Lu, Chuanyi M., Ott, Melanie, Wong, Joseph K., Yukl, Steven A.
Published in bioRxiv (2021)

Novel RT-ddPCR assays for simultaneous quantification of multiple noncoding and coding regions of SARS-CoV-2 RNA

by Telwatte, Sushama, Kumar, Nitasha, Vallejo-Gracia, Albert, Kumar, G. Renuka, Lu, Chuanyi M., Ott, Melanie, Wong, Joseph K., Yukl, Steven A.
Published in J Virol Methods (2021)

Mechanistic differences underlying HIV latency in the gut and blood contribute to differential responses to latency-reversing agents

by TELWATTE, Sushama, KIM, Peggy, CHEN, Tsui-Hua, MILUSH, Jeffrey M., SOMSOUK, Ma, DEEKS, Steven G., HUNT, Peter W., WONG, Joseph K., YUKL, Steven A.
Published in AIDS (2020)

Heterogeneity in HIV and cellular transcription profiles in cell line models of latent and productive infection: implications for HIV latency

by Telwatte, Sushama, Morón-López, Sara, Aran, Dvir, Kim, Peggy, Hsieh, Christine, Joshi, Sunil, Montano, Mauricio, Greene, Warner C., Butte, Atul J., Wong, Joseph K., Yukl, Steven A.
Published in Retrovirology (2019)

Novel RT-ddPCR assays for measuring the levels of subgenomic and genomic SARS-CoV-2 transcripts

by Telwatte, Sushama, Martin, Holly Anne, Marczak, Ryan, Fozouni, Parinaz, Vallejo-Gracia, Albert, Kumar, G. Renuka, Murray, Victoria, Lee, Sulggi, Ott, Melanie, Wong, Joseph K., Yukl, Steven A.
Published in Methods (2022)

Modification of the Abbott RealTime assay for detection of HIV-1 plasma RNA viral loads less than one copy per milliliter

by Yukl, Steven A., Li, Peilin, Fujimoto, Katsuya, Lampiris, Harry, Lu, Chuanyi M., Hare, C. Bradley, Deeks, Steven G., Liegler, Teri, Pandori, Mark, Havlir, Diane V., Wong, Joseph K.
Published 2011

Comparison of HIV DNA and RNA in Gut-Associated Lymphoid Tissue of HIV-Infected Controllers and Non-controllers

by Hatano, Hiroyu, Somsouk, Ma, Sinclair, Elizabeth, Harvill, Kara, Gilman, Lee, Cohen, Michelle, Hoh, Rebecca, Hunt, Peter W., Martin, Jeffrey N., Wong, Joseph K., Deeks, Steven G., Yukl, Steven A.
Published 2013

A Comparison of Methods for Measuring Rectal HIV Levels Suggests that HIV DNA Resides in Cells other than CD4+T Cells, Including Myeloid Cells

by Yukl, Steven A., Sinclair, Elizabeth, Somsouk, Ma, Hunt, Peter W., Epling, Lorrie, Killian, Maudi, Girling, Valerie, Li, Peilin, Havlir, Diane V., Deeks, Steven G., Wong, Joseph K., Hatano, Hiroyu
Published 2014

Effect of Raltegravir-containing Intensification on HIV Burden and T Cell Activation in Multiple Gut Sites of HIV+ Adults on Suppressive Antiretroviral Therapy

by Yukl, Steven A., Shergill, Amandeep, McQuaid, Kenneth, Gianella, Sara, Lampiris, Harry, Hare, C. Bradley, Pandori, Mark, Sinclair, Elizabeth, Günthard, Huldrych F., Fischer, Marek, Wong, Joseph K., Havlir, Diane V.
Published 2010

Site-Specific Differences in T Cell Frequencies and Phenotypes in the Blood and Gut of HIV-Uninfected and ART-Treated HIV+ Adults

by Yukl, Steven A., Shergill, Amandeep K., Girling, Valerie, Li, Qingsheng, Killian, Maudi, Epling, Lorrie, Li, Peilin, Kaiser, Philipp, Haase, Ashley, Havlir, Diane V., McQuaid, Kenneth, Sinclair, Elizabeth, Wong, Joseph K.
Published in PLoS One (2015)

Gut and blood differ in constitutive blocks to HIV transcription, suggesting tissue-specific differences in the mechanisms that govern HIV latency

by Telwatte, Sushama, Lee, Sulggi, Somsouk, Ma, Hatano, Hiroyu, Baker, Christopher, Kaiser, Philipp, Kim, Peggy, Chen, Tsui-Hua, Milush, Jeffrey, Hunt, Peter W., Deeks, Steven G., Wong, Joseph K., Yukl, Steven A.
Published in PLoS Pathog (2018)

Anti-HIV Antibody Responses and the HIV Reservoir Size during Antiretroviral Therapy

by Lee, Sulggi A., Bacchetti, Peter, Chomont, Nicolas, Fromentin, Remi, Lewin, Sharon R., O’Doherty, Una, Palmer, Sarah, Richman, Douglas D., Siliciano, Janet D., Yukl, Steven A., Deeks, Steven G., Burbelo, Peter D.
Published in PLoS One (2016)

Tissue‐specific differences in HIV DNA levels and mechanisms that govern HIV transcription in blood, gut, genital tract and liver in ART‐treated women

by Moron‐Lopez, Sara, Xie, Guorui, Kim, Peggy, Siegel, David A, Lee, Sulggi, Wong, Joseph K, Price, Jennifer C, Elnachef, Najwa, Greenblatt, Ruth M, Tien, Phyllis C, Roan, Nadia R, Yukl, Steven A
Published in J Int AIDS Soc (2021)

CD4(+) and CD8(+) T Cell Activation Are Associated with HIV DNA in Resting CD4(+) T Cells

by Cockerham, Leslie R., Siliciano, Janet D., Sinclair, Elizabeth, O'Doherty, Una, Palmer, Sarah, Yukl, Steven A., Strain, Matt C., Chomont, Nicolas, Hecht, Frederick M., Siliciano, Robert F., Richman, Douglas D., Deeks, Steven G.
Published 2014