Discovery of BIIB042, a Potent, Selective, and Orally Bioavailable γ-Secretase Modulator

Por Peng, Hairuo, Talreja, Tina, Xin, Zhili, Cuervo, J. Hernan, Kumaravel, Gnanasambandam, Humora, Michael J., Xu, Lin, Rohde, Ellen, Gan, Lawrence, Jung, Mi-young, Shackett, Melanie N., Chollate, Sowmya, Dunah, Anthone W., Snodgrass-belt, Pamela A., Arnold, H. Moore, Taveras, Arthur G., Rhodes, Kenneth J., Scannevin, Robert H.
Publicado em 2011

Germinal‐center kinase‐like kinase co‐crystal structure reveals a swapped activation loop and C‐terminal extension

Por Marcotte, Douglas, Rushe, Mia, M. Arduini, Robert, Lukacs, Christine, Atkins, Kateri, Sun, Xin, Little, Kevin, Cullivan, Michael, Paramasivam, Murugan, Patterson, Thomas A., Hesson, Thomas, D. McKee, Timothy, May‐Dracka, Tricia L., Xin, Zhili, Bertolotti‐Ciarlet, Andrea, Bhisetti, Govinda R., Lyssikatos, Joseph P., Silvian, Laura F.
Publicado no Protein Sci (2016)