Effects of flanking sequences and cellular context on subcellular behavior and pathology of mutant HTT

par Chongtham, Anjalika, Bornemann, Douglas J, Barbaro, Brett A, Lukacsovich, Tamas, Agrawal, Namita, Syed, Adeela, Worthge, Shane, Purcell, Judith, Burke, John, Chin, Theodore M, Marsh, J Lawrence
Publié dans Hum Mol Genet (2020)

Comparative study of naturally occurring huntingtin fragments in Drosophila points to exon 1 as the most pathogenic species in Huntington's disease

par Barbaro, Brett A., Lukacsovich, Tamas, Agrawal, Namita, Burke, John, Bornemann, Doug J., Purcell, Judith M., Worthge, Shane A., Caricasole, Andrea, Weiss, Andreas, Song, Wan, Morozova, Olga A., Colby, David W., Marsh, J. Lawrence
Publié dans Hum Mol Genet (2015)

Miles to go (mtgo) encodes FNDC3 proteins that interact with the chaperonin subunit CCT3 and are required for NMJ branching and growth in Drosophila

par Syed, Adeela, Lukacsovich, Tamás, Pomeroy, Miles, Bardwell, A. Jane, Decker, Gentry Thomas, Waymire, Katrina G., Purcell, Judith, Huang, Weijian, Gui, James, Padilla, Emily M., Park, Cindy, Paul, Antor, Pham, Thai Bin T., Rodriguez, Yanete, Wei, Stephen, Worthge, Shane, Zebarjedi, Ronak, Zhang, Bing, Bardwell, Lee, Marsh, J. Lawrence, MacGregor, Grant R.
Publié dans Dev Biol (2018)

A potent and selective Sirtuin 1 inhibitor alleviates pathology in multiple animal and cell models of Huntington's disease

par Smith, Marianne R., Syed, Adeela, Lukacsovich, Tamas, Purcell, Judy, Barbaro, Brett A., Worthge, Shane A., Wei, Stephen R., Pollio, Giuseppe, Magnoni, Letizia, Scali, Carla, Massai, Luisa, Franceschini, Davide, Camarri, Michela, Gianfriddo, Marco, Diodato, Enrica, Thomas, Russell, Gokce, Ozgun, Tabrizi, S.J., Caricasole, Andrea, Landwehrmeyer, Bernard, Menalled, Liliana, Murphy, Carol, Ramboz, Sylvie, Luthi-Carter, Ruth, Westerberg, Goran, Marsh, J. Lawrence
Publié 2014