Effects of flanking sequences and cellular context on subcellular behavior and pathology of mutant HTT

Por Chongtham, Anjalika, Bornemann, Douglas J, Barbaro, Brett A, Lukacsovich, Tamas, Agrawal, Namita, Syed, Adeela, Worthge, Shane, Purcell, Judith, Burke, John, Chin, Theodore M, Marsh, J Lawrence
Publicado no Hum Mol Genet (2020)

Comparative study of naturally occurring huntingtin fragments in Drosophila points to exon 1 as the most pathogenic species in Huntington's disease

Por Barbaro, Brett A., Lukacsovich, Tamas, Agrawal, Namita, Burke, John, Bornemann, Doug J., Purcell, Judith M., Worthge, Shane A., Caricasole, Andrea, Weiss, Andreas, Song, Wan, Morozova, Olga A., Colby, David W., Marsh, J. Lawrence
Publicado no Hum Mol Genet (2015)

Miles to go (mtgo) encodes FNDC3 proteins that interact with the chaperonin subunit CCT3 and are required for NMJ branching and growth in Drosophila

Por Syed, Adeela, Lukacsovich, Tamás, Pomeroy, Miles, Bardwell, A. Jane, Decker, Gentry Thomas, Waymire, Katrina G., Purcell, Judith, Huang, Weijian, Gui, James, Padilla, Emily M., Park, Cindy, Paul, Antor, Pham, Thai Bin T., Rodriguez, Yanete, Wei, Stephen, Worthge, Shane, Zebarjedi, Ronak, Zhang, Bing, Bardwell, Lee, Marsh, J. Lawrence, MacGregor, Grant R.
Publicado no Dev Biol (2018)

A potent and selective Sirtuin 1 inhibitor alleviates pathology in multiple animal and cell models of Huntington's disease

Por Smith, Marianne R., Syed, Adeela, Lukacsovich, Tamas, Purcell, Judy, Barbaro, Brett A., Worthge, Shane A., Wei, Stephen R., Pollio, Giuseppe, Magnoni, Letizia, Scali, Carla, Massai, Luisa, Franceschini, Davide, Camarri, Michela, Gianfriddo, Marco, Diodato, Enrica, Thomas, Russell, Gokce, Ozgun, Tabrizi, S.J., Caricasole, Andrea, Landwehrmeyer, Bernard, Menalled, Liliana, Murphy, Carol, Ramboz, Sylvie, Luthi-Carter, Ruth, Westerberg, Goran, Marsh, J. Lawrence
Publicado em 2014