Positive allosteric modulators as an approach to nicotinic acetylcholine receptor- targeted therapeutics: advantages and limitations

von Williams, Dustin K., Wang, Jingyi, Papke, Roger L.
Veröffentlicht 2011

Investigation of the Molecular Mechanism of the α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator PNU-120596 Provides Evidence for Two Distinct Desensitized States

von Williams, Dustin K., Wang, Jingyi, Papke, Roger L.
Veröffentlicht 2011

Differential Regulation of Receptor Activation and Agonist Selectivity by Highly Conserved Tryptophans in the Nicotinic Acetylcholine Receptor Binding Site

von Williams, Dustin K., Stokes, Clare, Horenstein, Nicole A., Papke, Roger L.
Veröffentlicht 2009

The effective opening of nicotinic acetylcholine receptors with single agonist binding sites

von Williams, Dustin K., Stokes, Clare, Horenstein, Nicole A., Papke, Roger L.
Veröffentlicht 2011

Development of repetitive behavior in a mouse model: Roles of indirect and striosomal basal ganglia pathways

von Tanimura, Yoko, King, Michael A., Williams, Dustin K., Lewis, Mark H.
Veröffentlicht 2011

Intrinsically Low Open Probability of α7 Nicotinic Acetylcholine Receptors Can Be Overcome by Positive Allosteric Modulation and Serum Factors Leading to the Generation of Excitoto...

von Williams, Dustin K., Peng, Can, Kimbrell, Matthew R., Papke, Roger L.
Veröffentlicht 2012