Kinetic Analysis and Probing with Substrate Analogues of the Reaction Pathway of the Nitrile Reductase QueF from Escherichia coli

Bằng Jung, Jihye, Czabany, Tibor, Wilding, Birgit, Klempier, Norbert, Nidetzky, Bernd
Xuất bản năm J Biol Chem (2016)

Demonstrating In-Cell Target Engagement Using a Pirin Protein Degradation Probe (CCT367766)

Bằng Chessum, Nicola E. A., Sharp, Swee Y., Caldwell, John J., Pasqua, A. Elisa, Wilding, Birgit, Colombano, Giampiero, Collins, Ian, Ozer, Bugra, Richards, Meirion, Rowlands, Martin, Stubbs, Mark, Burke, Rosemary, McAndrew, P. Craig, Clarke, Paul A., Workman, Paul, Cheeseman, Matthew D., Jones, Keith
Xuất bản năm J Med Chem (2017)

Investigating the phosphinic acid tripeptide mimetic DG013A as a tool compound inhibitor of the M1-aminopeptidase ERAP1

Bằng Wilding, Birgit, Pasqua, A. Elisa, E. A. Chessum, Nicola, Pierrat, Olivier A., Hahner, Tamas, Tomlin, Kathy, Shehu, Erald, Burke, Rosemary, Richards, G. Meirion, Whitton, Bradleigh, Arwert, Esther N., Thapaliya, Arjun, Salimraj, Ramya, van Montfort, Rob, Skawinska, Agi, Hayes, Angela, Raynaud, Florence, Chopra, Rajesh, Jones, Keith, Newton, Gary, Cheeseman, Matthew D.
Xuất bản năm Bioorg Med Chem Lett (2021)

Privileged Structures and Polypharmacology within and between Protein Families

Bằng Meyers, Joshua, Chessum, Nicola E. A., Ali, Salyha, Mok, N. Yi, Wilding, Birgit, Pasqua, A. Elisa, Rowlands, Martin, Tucker, Michael J., Evans, Lindsay E., Rye, Carl S., O’Fee, Lisa, Le Bihan, Yann-Vaï, Burke, Rosemary, Carter, Michael, Workman, Paul, Blagg, Julian, Brown, Nathan, van Montfort, Rob L. M., Jones, Keith, Cheeseman, Matthew D.
Xuất bản năm ACS Med Chem Lett (2018)

Discovery of a Chemical Probe Bisamide (CCT251236): An Orally Bioavailable Efficacious Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen

Bằng Cheeseman, Matthew D., Chessum, Nicola E. A., Rye, Carl S., Pasqua, A. Elisa, Tucker, Michael J., Wilding, Birgit, Evans, Lindsay E., Lepri, Susan, Richards, Meirion, Sharp, Swee Y., Ali, Salyha, Rowlands, Martin, O’Fee, Lisa, Miah, Asadh, Hayes, Angela, Henley, Alan T., Powers, Marissa, te Poele, Robert, De Billy, Emmanuel, Pellegrino, Loredana, Raynaud, Florence, Burke, Rosemary, van Montfort, Rob L. M., Eccles, Suzanne A., Workman, Paul, Jones, Keith
Xuất bản năm J Med Chem (2016)