Assessment of Beating Parameters in Human Induced Pluripotent Stem Cells Enables Quantitative In Vitro Screening for Cardiotoxicity

par Sirenko, Oksana, Cromwell, Evan F., Crittenden, Carole, Wignall, Jessica A., Wright, Fred A., Rusyn, Ivan
Publié 2013

Conditional Toxicity Value (CTV) Predictor: An In Silico Approach for Generating Quantitative Risk Estimates for Chemicals

par Wignall, Jessica A., Muratov, Eugene, Sedykh, Alexander, Guyton, Kathryn Z., Tropsha, Alexander, Rusyn, Ivan, Chiu, Weihsueh A.
Publié dans Environ Health Perspect (2018)

Standardizing Benchmark Dose Calculations to Improve Science-Based Decisions in Human Health Assessments

par Wignall, Jessica A., Shapiro, Andrew J., Wright, Fred A., Woodruff, Tracey J., Chiu, Weihsueh A., Guyton, Kathryn Z., Rusyn, Ivan
Publié 2014

In vitro cardiotoxicity assessment of environmental chemicals using an organotypic human induced pluripotent stem cell-derived model

par Sirenko, Oksana, Grimm, Fabian A., Ryan, Kristen R., Iwata, Yasuhiro, Chiu, Weihsueh A., Parham, Frederick, Wignall, Jessica A., Anson, Blake, Cromwell, Evan F., Behl, Mamta, Rusyn, Ivan, Tice, Raymond R.
Publié dans Toxicol Appl Pharmacol (2017)