Anti-apoptotic BCL-2 proteins govern cellular outcome following B-RAF(V600E) inhibition and can be targeted to reduce resistance

door Serasinghe, Madhavika N., Missert, Derek J., Asciolla, James J., Wieder, Shira Y., Podgrabinska, Simona, Izadmehr, Sudeh, Belbin, Gillian, Skobe, Mihaela, Chipuk, Jerry E.
Gepubliceerd in 2014

Activation of the Mitochondrial Fragmentation Protein DRP1 Correlates with BRAF(V600E) Melanoma

door Wieder, Shira Y., Serasinghe, Madhavika N., Sung, Julie C., Choi, Daniel C., Birge, Miriam B., Yao, Jonathan L., Bernstein, Emily, Celebi, Julide T., Chipuk, Jerry E.
Gepubliceerd in J Invest Dermatol (2015)

Outer mitochondrial membrane shape engages BAX α9 to initiate mitochondrial outer membrane permeabilization and apoptosis

door Renault, Thibaud T., Floros, Konstantinos V., Elkholi, Rana, Corrigan, Kelly-Ann, Kushnareva, Yulia, Wieder, Shira Y., Lindtner, Claudia, Serasinghe, Madhavika N., Asciolla, James J., Buettner, Christoph, Newmeyer, Donald D., Chipuk, Jerry E.
Gepubliceerd in Mol Cell (2014)

Immune biomarkers are more accurate in prediction of survival in ulcerated than in non-ulcerated primary melanomas

door de Moll, Ellen H., Fu, Yichun, Qian, Yingzhi, Perkins, Sara H., Wieder, Shira, Gnjatic, Sacha, Remark, Romain, Bernardo, Sebastian G., Moskalenko, Marina, Yao, Jonathan, Ferringer, Tammie, Chang, Rui, Chipuk, Jerry, Horst, Basil A., Birge, Miriam B., Phelps, Robert G., Saenger, Yvonne M.
Gepubliceerd in Cancer Immunol Immunother (2015)