MEK inhibition leads to BRCA2 downregulation and sensitization to DNA damaging agents in pancreas and ovarian cancer models

Autor Vena, Francesca, Jia, Ruochen, Esfandiari, Arman, Garcia-Gomez, Juan J., Rodriguez-Justo, Manuel, Ma, Jianguo, Syed, Sakeena, Crowley, Lindsey, Elenbaas, Brian, Goodstal, Samantha, Hartley, John A., Hochhauser, Daniel
Vydáno v Oncotarget (2018)

Targeting casein kinase 1 delta sensitizes pancreatic and bladder cancer cells to gemcitabine treatment by upregulating deoxycytidine kinase

Autor Vena, Francesca, Bayle, Simon, Nieto, Ainhoa, Quereda, Victor, Aceti, Massimiliano, Frydman, Sylvia M., Sansil, Samer S., Grant, Wayne, Monastyrskyi, Andrii, McDonald, Patricia, Roush, William R., Teng, Mingxiang, Duckett, Derek
Vydáno v Mol Cancer Ther (2020)