Regulatory Modeling and Simulation Moves Into the Next Gear in Europe

Por van der Graaf, P H
Publicado em 2013

What Pharmacometricians (Should) Do

Por van der Graaf, P H
Publicado em 2013

CPT: Pharmacometrics & Systems Pharmacology Publishes Its 100th Article

Por van der Graaf, P H, Friberg, L E
Publicado em 2014

Systems Pharmacology of the NGF Signaling Through p75 and TrkA Receptors

Por Toni, T, Dua, P, van der Graaf, P H
Publicado no CPT Pharmacometrics Syst Pharmacol (2014)

Systems Approaches Evolve Clinical Pharmacology

Por Waldman, S A, van der Graaf, P H, Terzic, A
Publicado em 2013

Analysis of the effects of alpha 1-adrenoceptor antagonists on noradrenaline-mediated contraction of rat small mesenteric artery.

Por Van der Graaf, P. H., Shankley, N. P., Black, J. W.
Publicado em 1996

Analysis of the activity of alpha 1-adrenoceptor antagonists in rat aorta.

Por Van der Graaf, P. H., Shankley, N. P., Black, J. W.
Publicado em 1996

Integrated Pharmacometrics and Systems Pharmacology Model-Based Analyses to Guide GnRH Receptor Modulator Development for Management of Endometriosis

Por Riggs, M M, Bennetts, M, van der Graaf, P H, Martin, S W
Publicado em 2012

Pharmacometrics and Systems Pharmacology Software Tutorials and Use: Comments and Guidelines for PSP Contributions

Por Vicini, P, Friberg, L E, van der Graaf, P H, Rostami-Hodjegan, A
Publicado em 2013

Exposure and characterization of the action of noradrenaline at dopamine receptors mediating endothelium-independent relaxation of rat isolated small mesenteric arteries.

Por Van der Graaf, P. H., Saxena, P. R., Shankley, N. P., Black, J. W.
Publicado em 1995

A Systems Pharmacology Perspective on the Clinical Development of Fatty Acid Amide Hydrolase Inhibitors for Pain

Por Benson, N, Metelkin, E, Demin, O, Li, G L, Nichols, D, van der Graaf, P H
Publicado em 2014

A hidden Markov model to assess drug-induced sleep fragmentation in the telemetered rat

Por Diack, C., Ackaert, O., Ploeger, B. A., van der Graaf, P. H., Gurrell, R., Ivarsson, M., Fairman, D.
Publicado em 2011

Systems Pharmacology Models Can Be Used to Understand Complex Pharmacokinetic-Pharmacodynamic Behavior: An Example Using 5-Lipoxygenase Inhibitors

Por Demin, O, Karelina, T, Svetlichniy, D, Metelkin, E, Speshilov, G, Demin Jr, O, Fairman, D, van der Graaf, P H, Agoram, B M
Publicado em 2013

Inter-study variability of preclinical in vivo safety studies and translational exposure–QTc relationships – a PKPD meta-analysis

Por Gotta, V, Cools, F, van Ammel, K, Gallacher, D J, Visser, S A G, Sannajust, F, Morissette, P, Danhof, M, van der Graaf, P H
Publicado no Br J Pharmacol (2015)