The conserved N-terminus of human rhinovirus capsid protein VP4 contains membrane pore-forming activity and is a target for neutralizing antibodies

Por Panjwani, Anusha, Asfor, Amin S., Tuthill, Tobias J.
Publicado no J Gen Virol (2016)

Cell Entry of the Aphthovirus Equine Rhinitis A Virus Is Dependent on Endosome Acidification

Por Groppelli, Elisabetta, Tuthill, Tobias J., Rowlands, David J.
Publicado em 2010

Characterization of Early Steps in the Poliovirus Infection Process: Receptor-Decorated Liposomes Induce Conversion of the Virus to Membrane-Anchored Entry-Intermediate Particles

Por Tuthill, Tobias J., Bubeck, Doryen, Rowlands, David J., Hogle, James M.
Publicado em 2006

Picornaviruses

Por Tuthill, Tobias J., Groppelli, Elisabetta, Hogle, James M., Rowlands, David J.
Publicado em 2010

Foot-and-Mouth Disease Virus Assembly: Processing of Recombinant Capsid Precursor by Exogenous Protease Induces Self-Assembly of Pentamers In Vitro in a Myristoylation-Dependent Ma...

Por Goodwin, Stewart, Tuthill, Tobias J., Arias, Armando, Killington, Richard A., Rowlands, David J.
Publicado em 2009

The Cellular Chaperone Heat Shock Protein 90 Is Required for Foot-and-Mouth Disease Virus Capsid Precursor Processing and Assembly of Capsid Pentamers

Por Newman, Joseph, Asfor, Amin S., Berryman, Stephen, Jackson, Terry, Curry, Stephen, Tuthill, Tobias J.
Publicado no J Virol (2018)

A plate-based high-throughput assay for virus stability and vaccine formulation

Por Walter, Thomas S., Ren, Jingshan, Tuthill, Tobias J., Rowlands, David J., Stuart, David I., Fry, Elizabeth E.
Publicado em 2012

Recombinant VP4 of Human Rhinovirus Induces Permeability in Model Membranes

Por Davis, Matthew P., Bottley, Graham, Beales, Lucy P., Killington, Richard A., Rowlands, David J., Tuthill, Tobias J.
Publicado em 2008

Deep Sequencing of Foot-and-Mouth Disease Virus Reveals RNA Sequences Involved in Genome Packaging

Por Logan, Grace, Newman, Joseph, Wright, Caroline F., Lasecka-Dykes, Lidia, Haydon, Daniel T., Cottam, Eleanor M., Tuthill, Tobias J.
Publicado no J Virol (2017)

Equine Rhinitis A Virus and Its Low pH Empty Particle: Clues Towards an Aphthovirus Entry Mechanism?

Por Tuthill, Tobias J., Harlos, Karl, Walter, Thomas S., Knowles, Nick J., Groppelli, Elisabetta, Rowlands, David J., Stuart, David I., Fry, Elizabeth E.
Publicado em 2009

Structures of foot and mouth disease virus pentamers: Insight into capsid dissociation and unexpected pentamer reassociation

Por Malik, Nayab, Kotecha, Abhay, Gold, Sarah, Asfor, Amin, Ren, Jingshan, Huiskonen, Juha T., Tuthill, Tobias J., Fry, Elizabeth E., Stuart, David I.
Publicado no PLoS Pathog (2017)

Picornavirus RNA is protected from cleavage by ribonuclease during virion uncoating and transfer across cellular and model membranes

Por Groppelli, Elisabetta, Levy, Hazel C., Sun, Eileen, Strauss, Mike, Nicol, Clare, Gold, Sarah, Zhuang, Xiaowei, Tuthill, Tobias J., Hogle, James M., Rowlands, David J.
Publicado no PLoS Pathog (2017)

Full Genome Sequencing Reveals New Southern African Territories Genotypes Bringing Us Closer to Understanding True Variability of Foot-and-Mouth Disease Virus in Africa

Por Lasecka-Dykes, Lidia, Wright, Caroline F., Di Nardo, Antonello, Logan, Grace, Mioulet, Valerie, Jackson, Terry, Tuthill, Tobias J., Knowles, Nick J., King, Donald P.
Publicado no Viruses (2018)

Capsid Protein VP4 of Human Rhinovirus Induces Membrane Permeability by the Formation of a Size-Selective Multimeric Pore

Por Panjwani, Anusha, Strauss, Mike, Gold, Sarah, Wenham, Hannah, Jackson, Terry, Chou, James J., Rowlands, David J., Stonehouse, Nicola J., Hogle, James M., Tuthill, Tobias J.
Publicado em 2014

Discrimination among Rhinovirus Serotypes for a Variant ICAM-1 Receptor Molecule

Por Xiao, Chuan, Tuthill, Tobias J., Bator Kelly, Carol M., Challinor, Lisa J., Chipman, Paul R., Killington, Richard A., Rowlands, David J., Craig, Alister, Rossmann, Michael G.
Publicado em 2004

Investigation of the Role of Protein Kinase D in Human Rhinovirus Replication

Por Guedán, Anabel, Swieboda, Dawid, Charles, Mark, Toussaint, Marie, Johnston, Sebastian L., Asfor, Amin, Panjwani, Anusha, Tuthill, Tobias J., Danahay, Henry, Raynham, Tony, Mousnier, Aurelie, Solari, Roberto
Publicado no J Virol (2017)

Within-Host Recombination in the Foot-and-Mouth Disease Virus Genome

Por Ferretti, Luca, Di Nardo, Antonello, Singer, Benjamin, Lasecka-Dykes, Lidia, Logan, Grace, Wright, Caroline F., Pérez-Martín, Eva, King, Donald P., Tuthill, Tobias J., Ribeca, Paolo
Publicado no Viruses (2018)

Genetic economy in picornaviruses: Foot-and-mouth disease virus replication exploits alternative precursor cleavage pathways

Por Herod, Morgan R., Gold, Sarah, Lasecka-Dykes, Lidia, Wright, Caroline, Ward, Joseph C., McLean, Thomas C., Forrest, Sophie, Jackson, Terry, Tuthill, Tobias J., Rowlands, David J., Stonehouse, Nicola J.
Publicado no PLoS Pathog (2017)

Irreversible inactivation of ISG15 by a viral leader protease enables alternative infection detection strategies

Por Swatek, Kirby N., Aumayr, Martina, Pruneda, Jonathan N., Visser, Linda J., Berryman, Stephen, Kueck, Anja F., Geurink, Paul P., Ovaa, Huib, van Kuppeveld, Frank J. M., Tuthill, Tobias J., Skern, Tim, Komander, David
Publicado no Proc Natl Acad Sci U S A (2018)

Structure of Ljungan virus provides insight into genome packaging of this picornavirus

Por Zhu, Ling, Wang, Xiangxi, Ren, Jingshan, Porta, Claudine, Wenham, Hannah, Ekström, Jens-Ola, Panjwani, Anusha, Knowles, Nick J., Kotecha, Abhay, Siebert, C. Alistair, Lindberg, A. Michael, Fry, Elizabeth E., Rao, Zihe, Tuthill, Tobias J., Stuart, David I.
Publicado no Nat Commun (2015)