Development of a novel DDS for site-specific PEGylated proteins

Por Yoshioka, Yasuo, Tsunoda, Shin-ichi, Tsutsumi, Yasuo
Publicado em 2011

Carbon Nanomaterials: Efficacy and Safety for Nanomedicine

Por Yamashita, Takuya, Yamashita, Kohei, Nabeshi, Hiromi, Yoshikawa, Tomoaki, Yoshioka, Yasuo, Tsunoda, Shin-ichi, Tsutsumi, Yasuo
Publicado no Materials (Basel) (2012)

Crystallization and preliminary X-ray analysis of the tumour necrosis factor α–tumour necrosis factor receptor type 2 complex

Por Mukai, Yohei, Nakamura, Teruya, Yoshioka, Yasuo, Tsunoda, Shin-ichi, Kamada, Haruhiko, Nakagawa, Shinsaku, Yamagata, Yuriko, Tsutsumi, Yasuo
Publicado em 2009

Evaluation of silica nanoparticle binding to major human blood proteins

Por Hata, Katsutomo, Higashisaka, Kazuma, Nagano, Kazuya, Mukai, Yohei, Kamada, Haruhiko, Tsunoda, Shin-ichi, Yoshioka, Yasuo, Tsutsumi, Yasuo
Publicado no Nanoscale Res Lett (2014)

Intravenous Administration of Polyethylene Glycol‐modified Tumor Necrosis Factor‐α Completely Regressed Solid Tumor in Meth‐A Murine Sarcoma Model

Por Tsutsumi, Yasuo, Kihira, Tetsunari, Tsunoda, Shin‐ichi, Kubo, Kazuyoshi, Miyake, Masaharu, Kanamori, Toshhiori, Nakagawa, Shinsaku, Mayumi, Tadanori
Publicado no Jpn J Cancer Res (1994)

A Novel Bispecific Antibody against Human CD3 and Ephrin Receptor A10 for Breast Cancer Therapy

Por Taki, Shintaro, Kamada, Haruhiko, Inoue, Masaki, Nagano, Kazuya, Mukai, Yohei, Higashisaka, Kazuma, Yoshioka, Yasuo, Tsutsumi, Yasuo, Tsunoda, Shin-ichi
Publicado no PLoS One (2015)

Creation of mouse TNFR2-selective agonistic TNF mutants using a phage display technique

Por Ando, Daisuke, Inoue, Masaki, Kamada, Haruhiko, Taki, Shintaro, Furuya, Takeshi, Abe, Yasuhiro, Nagano, Kazuya, Tsutsumi, Yasuo, Tsunoda, Shin-ichi
Publicado no Biochem Biophys Rep (2016)

Size and surface modification of amorphous silica particles determine their effects on the activity of human CYP3A4 in vitro

Por Imai, Shunji, Yoshioka, Yasuo, Morishita, Yuki, Yoshida, Tokuyuki, Uji, Miyuki, Nagano, Kazuya, Mukai, Yohei, Kamada, Haruhiko, Tsunoda, Shin-ichi, Higashisaka, Kazuma, Tsutsumi, Yasuo
Publicado no Nanoscale Res Lett (2014)

Asian Dust Particles Induce Macrophage Inflammatory Responses via Mitogen-Activated Protein Kinase Activation and Reactive Oxygen Species Production

Por Higashisaka, Kazuma, Fujimura, Maho, Taira, Mayu, Yoshida, Tokuyuki, Tsunoda, Shin-ichi, Baba, Takashi, Yamaguchi, Nobuyasu, Nabeshi, Hiromi, Yoshikawa, Tomoaki, Nasu, Masao, Yoshioka, Yasuo, Tsutsumi, Yasuo
Publicado em 2014

Expression of Eph receptor A10 is correlated with lymph node metastasis and stage progression in breast cancer patients

Por Nagano, Kazuya, Kanasaki, So-ichiro, Yamashita, Takuya, Maeda, Yuka, Inoue, Masaki, Higashisaka, Kazuma, Yoshioka, Yasuo, Abe, Yasuhiro, Mukai, Yohei, Kamada, Haruhiko, Tsutsumi, Yasuo, Tsunoda, Shin-ichi
Publicado em 2013

A trimeric structural fusion of an antagonistic tumor necrosis factor-α mutant enhances molecular stability and enables facile modification

Por Inoue, Masaki, Ando, Daisuke, Kamada, Haruhiko, Taki, Shintaro, Niiyama, Mayumi, Mukai, Yohei, Tadokoro, Takashi, Maenaka, Katsumi, Nakayama, Taisuke, Kado, Yuji, Inoue, Tsuyoshi, Tsutsumi, Yasuo, Tsunoda, Shin-ichi
Publicado no J Biol Chem (2017)

Effect of surface properties of silica nanoparticles on their cytotoxicity and cellular distribution in murine macrophages

Por Nabeshi, Hiromi, Yoshikawa, Tomoaki, Arimori, Akihiro, Yoshida, Tokuyuki, Tochigi, Saeko, Hirai, Toshiro, Akase, Takanori, Nagano, Kazuya, Abe, Yasuhiro, Kamada, Haruhiko, Tsunoda, Shin-ichi, Itoh, Norio, Yoshioka, Yasuo, Tsutsumi, Yasuo
Publicado em 2011

Intranasal exposure to amorphous nanosilica particles could activate intrinsic coagulation cascade and platelets in mice

Por Yoshida, Tokuyuki, Yoshioka, Yasuo, Tochigi, Saeko, Hirai, Toshiro, Uji, Miyuki, Ichihashi, Ko-ichi, Nagano, Kazuya, Abe, Yasuhiro, Kamada, Haruhiko, Tsunoda, Shin-ichi, Nabeshi, Hiromi, Higashisaka, Kazuma, Yoshikawa, Tomoaki, Tsutsumi, Yasuo
Publicado em 2013

Effective Cancer Targeting Using an Anti‐tumor Tissue Vascular Endotheliumspecific Monoclonal Antibody (TES‐23)

Por Wakai, Yukiko, Matsui, Junji, Koizumi, Keiichi, Tsunoda, Shin‐ichi, Makimoto, Hiroo, Ohizumi, Iwao, Taniguchi, Kenji, Kaiho, Shin‐ichi, Saito, Hiroyuki, Utoguchi, Naoki, Tsutsumi, Yasuo, Nakagawa, Shinsaku, Ohsugi, Yoshiyuki, Mayumi, Tadanori
Publicado no Jpn J Cancer Res (2000)

Amorphous nanosilica induce endocytosis-dependent ROS generation and DNA damage in human keratinocytes

Por Nabeshi, Hiromi, Yoshikawa, Tomoaki, Matsuyama, Keigo, Nakazato, Yasutaro, Tochigi, Saeko, Kondoh, Sayuri, Hirai, Toshiro, Akase, Takanori, Nagano, Kazuya, Abe, Yasuhiro, Yoshioka, Yasuo, Kamada, Haruhiko, Itoh, Norio, Tsunoda, Shin-ichi, Tsutsumi, Yasuo
Publicado em 2011

Promotion of allergic immune responses by intranasally-administrated nanosilica particles in mice

Por Yoshida, Tokuyuki, Yoshioka, Yasuo, Fujimura, Maho, Yamashita, Kohei, Higashisaka, Kazuma, Morishita, Yuki, Kayamuro, Hiroyuki, Nabeshi, Hiromi, Nagano, Kazuya, Abe, Yasuhiro, Kamada, Haruhiko, Tsunoda, Shin-ichi, Itoh, Norio, Yoshikawa, Tomoaki, Tsutsumi, Yasuo
Publicado em 2011

Hemopexin as biomarkers for analyzing the biological responses associated with exposure to silica nanoparticles

Por Higashisaka, Kazuma, Yoshioka, Yasuo, Yamashita, Kohei, Morishita, Yuki, Pan, Huiyan, Ogura, Toshinobu, Nagano, Takashi, Kunieda, Akiyoshi, Nagano, Kazuya, Abe, Yasuhiro, Kamada, Haruhiko, Tsunoda, Shin-ichi, Nabeshi, Hiromi, Yoshikawa, Tomoaki, Tsutsumi, Yasuo
Publicado em 2012

Intestinal absorption and biological effects of orally administered amorphous silica particles

Por Yoshida, Tokuyuki, Yoshioka, Yasuo, Takahashi, Hideki, Misato, Kazuki, Mori, Takahide, Hirai, Toshiro, Nagano, Kazuya, Abe, Yasuhiro, Mukai, Yohei, Kamada, Haruhiko, Tsunoda, Shin-ichi, Nabeshi, Hiromi, Yoshikawa, Tomoaki, Higashisaka, Kazuma, Tsutsumi, Yasuo
Publicado em 2014

Amorphous silica nanoparticles size-dependently aggravate atopic dermatitis-like skin lesions following an intradermal injection

Por Hirai, Toshiro, Yoshikawa, Tomoaki, Nabeshi, Hiromi, Yoshida, Tokuyuki, Tochigi, Saeko, Ichihashi, Ko-ichi, Uji, Miyuki, Akase, Takanori, Nagano, Kazuya, Abe, Yasuhiro, Kamada, Haruhiko, Itoh, Norio, Tsunoda, Shin-ichi, Yoshioka, Yasuo, Tsutsumi, Yasuo
Publicado em 2012

Cutaneous exposure to agglomerates of silica nanoparticles and allergen results in IgE-biased immune response and increased sensitivity to anaphylaxis in mice

Por Hirai, Toshiro, Yoshioka, Yasuo, Takahashi, Hideki, Ichihashi, Ko-ichi, Udaka, Asako, Mori, Takahide, Nishijima, Nobuo, Yoshida, Tokuyuki, Nagano, Kazuya, Kamada, Haruhiko, Tsunoda, Shin-ichi, Takagi, Tatsuya, Ishii, Ken J., Nabeshi, Hiromi, Yoshikawa, Tomoaki, Higashisaka, Kazuma, Tsutsumi, Yasuo
Publicado no Part Fibre Toxicol (2015)