Creation of mouse TNFR2-selective agonistic TNF mutants using a phage display technique

Tumor necrosis factor-α (TNF), which is an immuno-modulatory cytokine, has been suggested to cause inflammatory responses as well as protection against tissue dysfunction by binding two types of TNF receptor (TNFR1/TNFR2). However, the physiological effects of TNFR2-specific activation remain unclea...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Ando, Daisuke, Inoue, Masaki, Kamada, Haruhiko, Taki, Shintaro, Furuya, Takeshi, Abe, Yasuhiro, Nagano, Kazuya, Tsutsumi, Yasuo, Tsunoda, Shin-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5613346/
https://ncbi.nlm.nih.gov/pubmed/28955920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2016.06.008
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