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Amorphous nanosilica induce endocytosis-dependent ROS generation and DNA damage in human keratinocytes

BACKGROUND: Clarifying the physicochemical properties of nanomaterials is crucial for hazard assessment and the safe application of these substances. With this in mind, we analyzed the relationship between particle size and the in vitro effect of amorphous nanosilica (nSP). Specifically, we evaluate...

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Main Authors: Nabeshi, Hiromi, Yoshikawa, Tomoaki, Matsuyama, Keigo, Nakazato, Yasutaro, Tochigi, Saeko, Kondoh, Sayuri, Hirai, Toshiro, Akase, Takanori, Nagano, Kazuya, Abe, Yasuhiro, Yoshioka, Yasuo, Kamada, Haruhiko, Itoh, Norio, Tsunoda, Shin-ichi, Tsutsumi, Yasuo
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030505/
https://ncbi.nlm.nih.gov/pubmed/21235812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-8977-8-1
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