Cutaneous exposure to agglomerates of silica nanoparticles and allergen results in IgE-biased immune response and increased sensitivity to anaphylaxis in mice

BACKGROUND: The skin is a key route of human exposure to nanomaterials, which typically occurs simultaneously with exposure to other chemical and environmental allergen. However, little is known about the hazards of nanomaterial exposure via the skin, particularly when accompanied by exposure to oth...

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Detalhes bibliográficos
Publicado no:Part Fibre Toxicol
Main Authors: Hirai, Toshiro, Yoshioka, Yasuo, Takahashi, Hideki, Ichihashi, Ko-ichi, Udaka, Asako, Mori, Takahide, Nishijima, Nobuo, Yoshida, Tokuyuki, Nagano, Kazuya, Kamada, Haruhiko, Tsunoda, Shin-ichi, Takagi, Tatsuya, Ishii, Ken J., Nabeshi, Hiromi, Yoshikawa, Tomoaki, Higashisaka, Kazuma, Tsutsumi, Yasuo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482284/
https://ncbi.nlm.nih.gov/pubmed/26113229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-015-0095-3
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