The X-ray crystal structure of the catalytic domain of human neutrophil collagenase inhibited by a substrate analogue reveals the essentials for catalysis and specificity.

Por Bode, W, Reinemer, P, Huber, R, Kleine, T, Schnierer, S, Tschesche, H
Publicado em 1994

Reduction of matrix metalloproteinase 8-neutrophil collagenase levels during long-term doxycycline treatment of reactive arthritis.

Por Lauhio, A, Konttinen, Y T, Tschesche, H, Nordström, D, Salo, T, Lähdevirta, J, Golub, L M, Sorsa, T
Publicado em 1994

Fragmentation of human polymorphonuclear-leucocyte collagenase.

Por Knäuper, V, Osthues, A, DeClerck, Y A, Langley, K E, Bläser, J, Tschesche, H
Publicado em 1993

Collagenase in Sjögren's syndrome.

Por Konttinen, Y T, Kangaspunta, P, Lindy, O, Takagi, M, Sorsa, T, Segerberg, M, Tschesche, H, Eisen, A Z
Publicado em 1994

Membrane type 1 matrix metalloproteinase (MT1-MMP) cleaves the recombinant aggrecan substrate rAgg1mut at the 'aggrecanase' and the MMP sites. Characterization of MT1-MMP catabolic...

Por Büttner, F H, Hughes, C E, Margerie, D, Lichte, A, Tschesche, H, Caterson, B, Bartnik, E
Publicado em 1998

In vivo inhibition of human neutrophil collagenase (MMP-8) activity during long-term combination therapy of doxycycline and non-steroidal anti-inflammatory drugs (NSAID) in acute r...

Por Lauhio, A, Salo, T, Ding, Y, Konttinen, Y T, Nordström, D, Tschesche, H, Lähdevirta, J, Golub, L M, Sorsa, T
Publicado em 1994

Direct activation of human neutrophil procollagenase by recombinant stromelysin.

Por Knäuper, V, Wilhelm, S M, Seperack, P K, DeClerck, Y A, Langley, K E, Osthues, A, Tschesche, H
Publicado em 1993

Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor.

Por Fernandez-Catalan, C, Bode, W, Huber, R, Turk, D, Calvete, J J, Lichte, A, Tschesche, H, Maskos, K
Publicado em 1998

Assay of matrix metalloproteases types 8 and 9 by ELISA in human breast cancer.

Por Duffy, M. J., Blaser, J., Duggan, C., McDermott, E., O'Higgins, N., Fennelly, J. J., Tschesche, H.
Publicado em 1995

Fibroblast and neutrophil collagenases cleave at two sites in the cartilage aggrecan interglobular domain.

Por Fosang, A J, Last, K, Knäuper, V, Neame, P J, Murphy, G, Hardingham, T E, Tschesche, H, Hamilton, J A
Publicado em 1993

Neutrophil collagenase (MMP-8) cleaves at the aggrecanase site E373-A374 in the interglobular domain of cartilage aggrecan.

Por Fosang, A J, Last, K, Neame, P J, Murphy, G, Knäuper, V, Tschesche, H, Hughes, C E, Caterson, B, Hardingham, T E
Publicado em 1994

Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage.

Por Billinghurst, R C, Dahlberg, L, Ionescu, M, Reiner, A, Bourne, R, Rorabeck, C, Mitchell, P, Hambor, J, Diekmann, O, Tschesche, H, Chen, J, Van Wart, H, Poole, A R
Publicado em 1997